The new (liberal) eugenics

Despite the Nazi horrors, in 1953 the new eugenics was founded, when Watson and Crick postulated the double helix of DNA as the basis of chemical heredity. In 1961, scientists have deciphered the genetic code of DNA, laying the groundwork for code manipulation and the potential building of new life forms. After thirty years from the discovery of the DNA structure, the experimenters began to carry out the first clinical studies of human somatic cell therapy. The practice of prenatal genetic tests identifies genes or unwanted genetic markers. Parents can choose to continue pregnancy or give up the fetus. Once the preimplantation genetic diagnosis occurs, potential parents can choose to use in vitro fertilization and then test early embryonic cells to identify embryos with genes they prefer or avoid. Because of concerns about eugenics, genetic counseling is based on a "non-directive" policy to ensure respect for reproductive autonomy. The argument for this counseling service is that we should balance parental autonomy with child's autonomy in the future. Specialists have not yet given a clear answer to the question of whether these practices should be considered eugenic practices, or if they are moral practices. DOI: 10.13140/RG.2.2.28777.9584

Economic Effects of Bridal Ceremonies on Small Business Enterprises in USA: An exploratory Study

The wedding industry plays a significant role in the U.S. society and economy. The internal and external treats of the wedding industry remain one of the major issues the industry is encountering. The current intense competition and declining marriage rates remain vital challenges and must be well managed to stimulate the industry growth. This research is investigating the motives behind the industry challenges to propose the most efficient solutions and overcome these underperformances. Our research data reveals that the rapid development and utilization of technology have increased wedding costs, inspired labor market changes and raised moral laxity in society. Hence, the collaboration between small business enterprises and the US government is imperative to instigate the industry expansion. Keywords: wedding, bridal ceremonies, small business, vertical integration, instigat

Methods for detection and characterization of signals in noisy data with the Hilbert-Huang Transform

The Hilbert-Huang Transform is a novel, adaptive approach to time series analysis that does not make assumptions about the data form. Its adaptive, local character allows the decomposition of non-stationary signals with hightime-frequency resolution but also renders it susceptible to degradation from noise. We show that complementing the HHT with techniques such as zero-phase filtering, kernel density estimation and Fourier analysis allows it to be used effectively to detect and characterize signals with low signal to noise ratio.Comment: submitted to PRD, 10 pages, 9 figures in colo

Synthesis of a Model of the BC Ring System of Oxygenated Angucyclines

Angucycline is a subclass of natural antibiotics, containing a characteristic tetracyclic ring structure, and featuring a wide range of biological functions, including antitumor, antiviral and antifungal properties. This extraordinarily therapeutic character has interested many chemists to develop efficient methodologies for synthesizing the tetracyclic ring system of angucycline. Construction of the BC ring configuration appears as a synthetic challenge. Successful installation of hydroxyl groups at the AB junction would pave the way for efficient syntheses. As a continuation of the previous work done on this system, our synthetic methodology focuses on the coupling of a suitably substituted Phthalide and an activated Alkyne through a tandem Michael addition/Dieckmann cyclization. The synthesis of the required phthalide and alkyne components is discussed, as well as our efforts towards the coupling components

Influence of ionospheric perturbations in GPS time and frequency transfer

The stability of GPS time and frequency transfer is limited by the fact that GPS signals travel through the ionosphere. In high precision geodetic time transfer (i.e. based on precise modeling of code and carrier phase GPS data), the so-called ionosphere-free combination of the code and carrier phase measurements made on the two frequencies is used to remove the first-order ionospheric effect. In this paper, we investigate the impact of residual second- and third-order ionospheric effects on geodetic time transfer solutions i.e. remote atomic clock comparisons based on GPS measurements, using the ATOMIUM software developed at the Royal Observatory of Belgium (ROB). The impact of third-order ionospheric effects was shown to be negligible, while for second-order effects, the tests performed on different time links and at different epochs show a small impact of the order of some picoseconds, on a quiet day, and up to more than 10 picoseconds in case of high ionospheric activity. The geomagnetic storm of the 30th October 2003 is used to illustrate how space weather products are relevant to understand perturbations in geodetic time and frequency transfer.Comment: 25 pages, 10 eps figures, 1 table, accepted in Journal of Advances in Space Research, Special Issue "Recent advances in space weather monitoring, modelling and forecasting